SIADH vs Diabetes Insipidus (DI) for nursing endocrine system lecture exams and NCLEX review. This easy explanation on SIADH vs DI helps simplify the pathophysiology of diabetes insipidus and Syndrome of Inappropriate Anti-diuretic hormone. The key to understanding diabetes insipidus and SIADH is how the anti-diuretic hormone (ADH) works on the body. The ADH hormone is produced in the hypothalamus and secreted/stored in the posterior pituitary gland. ADH is responsible for retaining water in the body and constricting blood vessels. In SIADH, there is hypersecretion of ADH and hypo-secretion of ADH in Diabetes Insipidus. Learn more about the signs and symptoms and nursing interventions/management for SIADH and DI.
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